7. Add another medication to view potential interactions with this medication. Common interactions include back pain among females and diarrhoea among males. You take your dose of medication, and let's say that your body starts with 100 units of that drug in every drop of . Call your doctor at once if you have any of these symptoms. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. drug. You may take losartan either with food or on an empty stomach. The phase IV clinical study analyzes what interactions people who take Losartan and Multivitamin have. Losartan is typically taken by mouth in the following dosages, according to the condition being treated. The most regularly reported side effect of this medication is an increase in infections such as colds or the flu which occurs in up to 8 percent of users.Other side effects reported more commonly include dizziness in up to 3 percent of users, nasal congestion in 2 percent and back pain in 2 percent of . This does not necessarily mean no interactions exist. It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Drugs or supplements that contain potassium . . Always consult your healthcare provider. About half of U.S. adults report taking supplements. Experts have not recorded major interactions between hydrochlorothiazide and vitamins. A A. can i take a multivitamin and a b complex vitamin with it? Consult your healthcare professional (e.g., doctor or pharmacist) for. Losartan is approximately 33% orally bioavailable. This, in turn, can improve the quality and duration of erections. It might help strengthen the heartbeat, which could benefit people with certain heart conditions. Taking both spironolactone and Cozaar ( losartan) together increases the risk of hyperkalemia (high potassium levels). It is created by eHealthMe based on reports of 3,221 people who take Losartan and Multivitamin from the FDA, and is updated regularly. The side effects may bear both temporary or long-term character, which a patient should address to their healthcare provider. Losartan has relatively mild side effects, including headache, cough, stomach pain, heart palpitations, and dizziness when standing. They typically result from the wrong intake of the medication or interactions. The active metabolite would take longer, ranging from 12 to 18 hours to completely be eliminated from the bloodstream. 1 . Answer. Like other medications, Losartan side effect events are common. Different interactions can cause different effects. Are the Drugs You Take Making You Lose Essential Vitamins and Minerals? Methods: Thirty-two Wistar rats were divided into 5 groups: group 1 receiving losartan 10 mg/kg; group 2, vitamin E in almond oil 1 g/kg; group 3, combination of group 1 and 2 regimens; group 4, almond oil; and . One of losartan's "positive" side effects (and other ARBs) is their effects on moods. Drug interactions are reported among people who take Losartan and Vitamin c. Common interactions include drug ineffective among females and diarrhoea among males. Losartan is used to treat high blood pressure (hypertension) and to help protect the kidney from damage due to diabetes. Losartan Interaction with 692 drugs. Alcohol can increase the risk for low blood pressure and dizziness. It is also used to lower the risk of stroke in certain people with heart disease. Losartan Vitamin d and Losartan drug interactions - a phase IV clinical study of FDA data Summary: Drug interactions are reported among people who take Vitamin d and Losartan. The dose should be increased to 100 mg PO once daily based on blood pressure response. 1,3,4 Losartan has a T max of 1 hour and the active metabolite has a T max of 3-4 hours. Do not take Cozaar if pregnant or . These alterations can be related to a lack of differentiation of these tubular cells 9 - 13. Losartan interaction: The main interaction with Losartan would be taking any large amount of Potassium, which may be a part of your multivitamin.I might also be concerned that you want to take both a multivitamin and a B-complex vitamin. However, the regular, dietary turmeric intake is safe to include. In the long-term (mean 3.4 years) RENAAL study, losartan (50 to 100 mg/day PO) was renoprotective (end points: doubling of serum creatinine, development of end-stage renal disease) vs. placebo in hypertensive patients with type 2 diabetes and nephropathy (urinary albumin to . Patients with these risk factors should be targeted for interventions to prevent drug interactions with vitamins and minerals. Because of this, there is a potential for interactions with some common drugs. Common side effects of losartan include stuffy nose, back pain, and dizziness. This type of blood pressure medication also treats heart . Zestoretic is a good 2-in-1 blood pressure medication that also protects kidney function long-term. I take losartan 50mg for blood pressure. Anyone who is taking amlodipine and valsartan and develops a fever, muscle pain, muscle weakness, excessive fatigue, or dark-colored urine should call their doctor right away. It is created by eHealthMe based on reports of 4,693 people who take Losartan and Vitamin b12 from the FDA, and is updated regularly. Hence, it is best to not take curcumin supplements with Losartan. Losartan potassium and hydrochlorothiazide tablets and certain other medicines may interact with each . vitamins, and herbal supplements. Patients taking fluconazole should be given the lowest possible Celebrex dose. Spironolactone is known as a 'potassium-sparing diuretic . Symptoms of high potassium levels include: Muscle weakness. Absorption. Losartan Potassium: No clinically significant drug interactions have been found in studies of losartan potassium with hydrochlorothiazide, digoxin, warfarin, cimetidine and phenobarbital. It is created by eHealthMe based on reports the from the FDA, and is updated regularly. Herbal supplements can have strong effects in the body. Learn more about Losartan (Cozaar) at EverydayHealth.com. Losartan potassium is a prescription drug used to treat hypertension (high blood pressure). Before adding it to your diet, check with your healthcare provider if you take medications. Fact Checked. The metabolite half-life of Losartan is between six to nine hours. Different interactions can cause different effects. The Food and Drug Administration warns that taking dietary supplements with silver can cause the body to have greater difficulty absorbing certain drugs, including quinolone . . Dr. Susan Madonna answered Family Medicine 22 years experience Losartan interaction: The main interaction with Losartan would be taking any large amount of Potassium, which may be a part of your multivitamin. Lisinopril & Hydrochlorothiazide is therefore a valuable therapy in the field of internal medicine is a prescription medication used to treat high blood pressure. Think of the half-life of a drug this way. 1,3,4 A 50-80mg oral dose of losartan leads to a C max of 200-250ng/mL. It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart. Potential is there for excess B vitamins.If possible, have a consultation with your pharmacist to discuss the specific multivitamin and possible interactions. But research suggests that most don't tell . Side effects for those suffering from Losartan are not very common. Estimates show that between 40% and 60% of U.S. adults with chronic disease use dietary supplements, and among patients taking prescription medications, an estimated 20% to 25% concurrently use a . Diuretics - NSAIDs, including Celebrex, can reduce the diuretic effect of furosemide and thiazides in some patient. Common side effects of Cozaar include chest pain, diarrhea, dizziness, fatigue, insomnia, low blood sugar (hypoglycemia), muscle cramps, nasal congestion, urinary tract infections (UTIs), and weakness. Drug and Food Interactions Close all sections. Losartan is an angiotensin II receptor blocker (ARB), prescribed for high blood pressure. painkillers such as ibuprofen, naproxen, diclofenac, celecoxib or etoricoxib. For more information, please visit our page on hydrochlorothiazide and alcohol interactions. May make these conditions worse. The phase IV clinical study analyzes what interactions people who take Losartan and B complex vitamin have. Does LOSARTAN POTASSIUM Interact with other Medications? Drug interactions with grapefruit juice are well documented. A total of 294 medications are known to interact with losartan . In some patients grapefruits and grapefruit juice may decrease the efficacy of losartan. Vitamins. The phase IV clinical study analyzes what interactions people who take Losartan and Vitamin k have. 5. Find out more in the list below: Chest pain. We would like to show you a description here but the site won't allow us. Vitamins D, E and K. "Studies have shown that a person's absorption of Vitamin K may be reduced when other fat-soluble vitamins such as Vitamin E and Vitamin D are taken together," says Dr . High levels of potassium can cause weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs. Summary of Interactions with Vitamins, Herbs, & Foods What Are Nutrient Interactions Types of interactions: Beneficial Adverse Check Replenish Depleted Nutrients Zinc Reduce Side Effects none Support Medicine none Reduces Effectiveness Grapefruit Potential Negative Interaction Potassium Explanation Required none Treatment with calcitriol attenuated -SMA expression and increased cubulin . A recent study suggested that milk thistle . Interactions with drugs or supplements. Although vitamins C and E and losartan have antioxidant effects [22, 23, 38, 39], losartan itself acts as a blocker of angiotensin II receptor 1 (ATR1), which facilitates renal circulation [40, 41]. On the other hand, one form of magnesium may increase the absorption of certain anti-diabetes drugs such as glibenclamide (DiaBeta, Micronase, Glynase) and glimepiride (Amaryl), potentially affecting blood sugar control. This effect has been associated to the . Goldenseal appears to inhibit some cytochrome P450 (CYP) drug-metabolizing isozymes, CYP3A4, CYP2D6, and probably CYP2C9. . It is also used to reduce the risk of stroke in high blood pressure and enlarged heart patients. Common interactions include drug ineffective among females and drug ineffective among males. There is no drug interaction reported. Because CYP3A4 metabolizes more drugs than any other isozyme, there is a potential for numerous interactions with goldenseal. Losartan/hydrochlorothiazide is a prescription drug that's used to treat high blood pressure (hypertension). Promptly consult your doctor or pharmacist. Common interactions include malaise among females and fatigue among males. This medication helps the blood vessels to relax and eventually widen. Losartan + Food The following applies to the ingredients: Losartan . Risk factors for poor outcomes from drug interactions include use of multiple medications and/or supplements, older age, inadequate kidney or liver function, and the use of medications with narrow therapeutic indexes. Lisinopril/Hydrochlorothiazide is therefore a valuable therapy in the field of internal medicine. Berberine is a chemical found in some plants like European barberry, goldenseal, goldthread, Oregon grape, phellodendron, and tree turmeric. If the blood pressure drops too low, you may feel dizzy or faint, in some cases falls or . This medication comes in tablet form and is usually taken once or twice daily. I might also be concerned . Some can interact with prescription medications used to treat heart and circulatory problems, such as high blood pressure and heart failure. Common medications causing interactions with ACE inhibitors include aspirin, ibuprofen, naproxen and potassium supplements 2. Lastly, Losartan 50 MG Tablet is used for treating diabetic nephropathy, a kidney disease caused due to diabetes. Read More As far as Amlodipine is concerned, there is no conclusive evidence pointing towards . . For adults 50 mg per day is a recommended dose. Before taking colloidal silver supplements, you should be aware there are some moderate interactions that may occur between the supplements and certain drugs. Abnormal heart rhythm. Other potential serious effects of taking amlodipine and valsartan include: Syncope (passing out) Swelling. The phase IV clinical study analyzes what interactions people who take Losartan and Vitamin b12 have. No drug interactions were found for selected drugs: losartan, Vitamin B12. 1,3,4 Taking losartan with food decreases the C max but does only results in a 10% decrease in the AUC of losartan and its active metabolite. You can use the study as a second opinion to make health care decisions. The protective effect of losartan against CP-induced nephrotoxicity was reported before [5, 6], and it has no effect on CP uptake by the kidney . As soon as a patient's body gets used to the drug, side effects are rare or . Some of these interactions can even be dangerous. Palpitations. Children: Starting at 0.7 mg per kilogram of weight per day, up to 50 mg. Hypertensive patients with enlarged heart have a usual starting dose of 50 mg a day. Fever. Both Losartan and Spironolactone can increase the risk of hypotension. There is an interaction between these two drugs. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hypertension: Adults: 50 milligrams (mg) a day. 50 mg PO once daily, initially. Common Interactions Checks Aspir 81 Aspirin Low Strength CoQ10 Eliquis Fish Oil Metoprolol Succinate ER Metoprolol Tartrate Synthroid Tylenol Vitamin B12 Vitamin C Vitamin D3 Drug and Food Interactions Both Losartan and Spironolactone can increase the risk of hyperkalaemia (hyperkalaemia is particularly notable when ACE inhibitors or angiotensin-II receptor antagonists are given with spironolactone or eplerenone). Severe Interactions These medications are not usually taken together. Don't . Losartan belongs to a class of drugs called . Rats exposed to losartan also showed reduction of cubulin in the cells of proximal tubules, the receptor responsible for resorption of Vitamin D, compared to the controls. Fluconazole is thought to interfere with the metabolism of celecoxib, particularly in the P450 2C9 pathway. Losartan (Cozaar) is another antihypertensive that may work in combination with hydrochlorothiazide to treat hypertension and lower the risk of stroke; . The phase IV clinical study analyzes what interactions people who take Losartan and Vitamin c have. Moderate. Argyria, The Disfiguring Disease Caused By Colloidal Silver Products ; Alternative Treatment: 6 Vitamins And Nutritional Supplements For High Cholesterol ; How to Store Food and Preserve Vitamins The phase IV clinical study analyzes what interactions people who take Losartan and Vitamin e have. Grapefruits and grapefruit juice should be avoided if . . Notes for Consumers: It is best to limit your intake of alcohol while taking this drug. Grapefruit is a source of vitamin C, fiber, potassium, pectin, and other nutrients. Avoid grapefruit unless MD instructs otherwise. Reducing hypertension helps in preventing stroke, heart attack and kidney problems. These drugs include: nonsteroidal anti-inflammatory drugs that are used to treat pain and . Losartan Side Effects. Cozaar (losartan) is a prescription medication used to treat high blood pressure (hypertension), reduce stroke risk, and prevent kidney damage from diabetes. Summary: We study 130,214 people who take Losartan or B complex vitamin. Chills. Find everything you need to know about Losartan (Cozaar), including what it is used for, warnings, reviews, side effects, and interactions. Available clinical evidence suggests that goldenseal does not inhibit CYP1A2 or CYP2E1, and the . Drug Interactions. Read More. Berberine is a bitter-tasting and yellow-colored chemical. Interactions between losartan (Cozaar) and other medications Losartan (Cozaar) may interact with certain medications or supplements. People use the fruit, oil from the peel, and extracts as medicine. Spironolactone. Losartan has caused significant increases in blood potassium levels. Losartan is available in the form of tablet to be taken once or twice a day. Potassium supplements, potassium-containing salt substitutes (No Salt, Morton Salt Substitute, and others), and even high-potassium foods (including Noni juice) should be avoided by those taking losartan, unless directed otherwise by their doctor. The blood pressure lowering effect of losartan may be opposed by medicines that have the potential to increase your blood pressure, such as the following: regular use of non-steroidal anti . USES: Losartan is used to treat high blood pressure (hypertension) and to help protect the kidneys from damage due to diabetes. Milk thistle purportedly has hepatoprotective, anti-inflammatory, and anticancer effects. Losartan (Cozaar) It is created by eHealthMe based on reports of 1,034 people who take Losartan and Vitamin e from the FDA, and is updated regularly. Liver disease (including cirrhosis)Use with caution. Dosage. Vitamin D regulates the amount of minerals such as calcium in the body 1. Electrolyte imbalances (eg, high or low potassium or sodium in the body)Use with caution. Drug interactions are reported among people who take Losartan and Vitamin k. Common interactions include pain in extremity among females and headache among males. Find patient medical information for Losartan-Hydrochlorothiazide Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Some medicines can affect the way losartan works. Losartan 50 MG Tablet blocks the action of the chemical named angiotension II in the body, which causes the blood vessels to narrow and tighten. Vitamin D is essential to maintaining a healthy immune system and strong bones. Losartan belongs to a group of drugs called angiotensin II receptor antagonists. Drugs or supplements that . The present study was designed to compare the effect of losartan and vitamin E as prophylaxes against CDDP-induced nephrotoxicity. There exists a small but definite possibility of interaction between curcumin supplement and the anti-hypertensive drug, Losartan. The effects may be increased because of slower removal of losartan from the body. Tell your doctor if you're taking: other medicines to help lower your blood pressure, including aliskiren, enalapril, captopril, lisinopril or ramipril. Description and Brand Names. In some cases, magnesium can still be taken, but only several hours before or after taking these drugs. The extract of the seeds of milk thistle contains a number of substances, collectively called silymarin. aspirin more than 3g a day. Kidney disease or. Losartan belongs a group of drugs called angiotensin receptor blockers (ARBs), which help lower blood pressure by relaxing blood vessels. Levothyroxine (l-thyroxine, l-T4) is a drug of choice for treating congenital and primary hypothyroidism.Although clinically significant interactions between l-T4 and food can alter the safety and efficacy of the treatment, they still seem to be generally underestimated by patients, physicians and pharmacists.This review aimed to investigate the effects of meals, beverages, and dietary . Losartan is a type of blood pressure medication that works by blocking receptors for angiotensin, an enzyme that can cause blood pressure to increase. Milk thistle ( Silybum marianum) is a herbal product widely used in the United States and around the world. Losartan oral tablets can interact with several types of drugs.